Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZGLP1 P0C6A0 zinc finger GATA like protein 1 0.39 0.512 0.808
XPR1 Q9UBH6 xenotropic and polytropic retrovirus receptor 1 Transporter 1.00 0.488 0.731
VLDLR P98155 very low density lipoprotein receptor 2.0E-11 0.558 0.692
TRAF6 Q9Y4K3 TNF receptor associated factor 6 Signaling 1.00 0.472 0.808
TNFSF13B Q9Y275 TNF superfamily member 13b 0.98 0.460 0.731
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
TNFRSF10B O14763 TNF receptor superfamily member 10b 2.0E-04 0.505 0.769
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR9 Q9NR96 toll like receptor 9 9.8E-06 0.411 0.885
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
SREBF2 Q12772 sterol regulatory element binding transcription factor 2 0.21 0.566 0.577
SREBF1 P36956 sterol regulatory element binding transcription factor 1 1.5E-02 0.518 0.808
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SMPD1 P17405 sphingomyelin phosphodiesterase 1 Enzyme 3.9E-10 0.499 0.885
SLC5A2 P31639 solute carrier family 5 member 2 Transporter 4.9E-14 0.499 0.769
SLC17A5 Q9NRA2 solute carrier family 17 member 5 Transporter 6.9E-10 0.491 0.808
SLC11A2 P49281 solute carrier family 11 member 2 Transporter 6.7E-03 0.566 0.769
SLC10A2 Q12908 solute carrier family 10 member 2 Transporter 9.6E-17 0.621 0.538
SIRT6 Q8N6T7 sirtuin 6 Epigenetic regulator 3.9E-02 0.496 0.846
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SI P14410 sucrase-isomaltase Enzyme 3.9E-60 0.569 0.692
SCARB1 Q8WTV0 scavenger receptor class B member 1 Receptor 6.6E-02 0.559 0.731